Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409399 | 1.00 | DRD4 (0.34) | DRD4TSHRHSD17B10HPGDCYP3A4 | |
| SCHEMBL23409587 | 0.80 | HSD17B10 (0.38) | TSHRHSD17B10HPGDCYP3A4HSP90AA1 | |
| SCHEMBL29970962 | 0.80 | HSD17B10 (0.38) | TSHRHSD17B10HPGDCYP3A4HSP90AA1 | |
| SCHEMBL29970956 | 0.77 | TSHR (0.33) | TSHRHSD17B10HPGDCYP3A4HSP90AA1 | |
| SCHEMBL23409465 | 0.77 | TSHR (0.33) | TSHRHSD17B10HPGDCYP3A4HSP90AA1 | |
| SCHEMBL23409499 | 0.73 | DRD4 (0.30) | DRD4 | |
| SCHEMBL29969345 | 0.73 | DRD4 (0.30) | DRD4 | |
| SCHEMBL23409568 | 0.69 | HSD17B10 (0.54) | TSHRHSD17B10HPGDCYP3A4HSP90AA1 | |
| SCHEMBL23409459 | 0.68 | TAAR1 (0.33) | HSD17B10CYP3A4 | |
| SCHEMBL23287117 | 0.68 | NMT1 (0.32) | MEN1LMNAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279359-A | Novel thyromimetic agents | 速通医疗公司 | 2022-11-01 | — | — | CN | disclosed |