Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22089477 | 1.00 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL3469757 | 0.84 | CYP3A4 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL5940300 | 0.84 | HSD17B10 (0.52) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL27129026 | 0.80 | RAPGEF4 (0.39) | CYP3A4CHRM1ALOX15TBXA2RADRA1A | |
| SCHEMBL20561941 | 0.77 | HTR1D (0.35) | SIRT1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30937162 | 0.77 | HTR1D (0.35) | SIRT1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22106260 | 0.75 | CYP3A4 (0.39) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL12401840 | 0.75 | HTR1D (0.47) | CYP3A4CHRM1ADRA1AHTR2BALDH1A1 | |
| SCHEMBL4681948 | 0.74 | TAAR1 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL16095665 | 0.74 | HSD17B10 (0.42) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279359-A | Novel thyromimetic agents | 速通医疗公司 | 2022-11-01 | — | — | CN | disclosed |