Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22089476 | 0.84 | CYP3A4 (0.39) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL22089477 | 0.84 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL29970906 | 0.84 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL29971161 | 0.84 | CYP3A4 (0.39) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL18073446 | 0.82 | CYP3A4 (0.38) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL95192 | 0.80 | HRH3 (0.40) | ACHEALDH1A1TDP1KDM4EGAA | |
| SCHEMBL892872 | 0.80 | CA1 (0.48) | CYP3A4ALDH1A1SHBGSMN1; SMN2TDP1 | |
| SCHEMBL675857 | 0.80 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL22095632 | 0.79 | CYP3A4 (0.35) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL6285400 | 0.78 | CYP3A4 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378268-B2 | Heterocyclic THR-β receptor agonist compound and preparation method and use therefor | Hepagene Therapeutics (HK) Limited (CN) | 2025-08-05 | — | — | US | disclosed |
| US-20230416460-A1 | COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED PRODUCT, AND LAMINATED SUBSTRATE | TDK CORPORATION (JP) | 2023-12-28 | — | — | US | disclosed |
| US-11827596-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| CN-116490355-A | Compound, resin composition, resin sheet, resin cured product, and laminated substrate | TDK株式会社 | 2023-07-25 | — | — | CN | disclosed |
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| WO-2022209495-A1 | COMPOUND, RESIN COMPOSITION, RESIN SHEET, RESIN CURED OBJECT, AND LAMINATED SUBSTRATE | TDK株式会社 | 2022-10-06 | — | — | WO | disclosed |
| US-20220298187-A1 | HETEROCYCLIC THR-B RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREFOR | HEPAGENE THERAPEUTICS HK LTD (CN) | 2022-09-22 | — | — | US | disclosed |
| CN-112457346-B | Fused-ring THR beta receptor agonist compound and preparation method and application thereof | 和博医药有限公司 | 2022-09-06 | — | — | CN | disclosed |
| EP-4019524-A1 | HETEROCYCLIC THR-BETA RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREFOR | Hepagene Therapeutics (HK) Limited (HK) | 2022-06-29 | — | — | EP | disclosed |
| US-10420781-B2 | Thyroid hormone receptor agonist and use thereof | METABASIS THERAPEUTICS INC. (US) | 2019-09-24 | — | — | US | disclosed |
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| CN-1234706-C | Nitrogen-oxygen heterocyclic compound and preparation method thereof | CHANGCHUN ARTIFICIAL RESIN FAC (CN) | 2006-01-04 | — | — | CN | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| CN-1490318-A | Nitrogen-oxygen heterocyclic compound and preparation method thereof | 长春人造树脂厂股份有限公司 | 2004-04-21 | — | — | CN | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
| US-6211328-B1 | IN PRESENCE OF AN ACID | GUN EI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-04-03 | — | — | US | disclosed |
| US-4233431-A | HEAT AND CHEMICAL RESISTANT STABILIZERS-POLYCARBONATE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4142035-A | Polycondensates containing hydroxyquinoline end groups, their use for the preparation of polymers containing metals and metal containing polycondensates | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4137219-A | STABILIZERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-3983160-A | Process for the preparation of hydroxyphenylacetonitriles | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | CYP3A4 1456/4885CHRM1 2049/4885ALOX15 228/4885 |
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | CYP3A4 918/4885CHRM1 5/4885ALOX15 1864/4885 |
| US-10420781-B2 | Thyroid hormone receptor agonist and use thereof | THRB, THRA, TSHR | CYP3A4 1018/4885CHRM1 911/4885ALOX15 2864/4885 |
| US-12378268-B2 | Heterocyclic THR-β receptor agonist compound and preparation method and use therefor | THRB, THRA, ADRB1 | CYP3A4 1105/4885CHRM1 543/4885ALOX15 2319/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | CYP3A4 1249/4885CHRM1 2316/4885ALOX15 219/4885 |
| US-20220298187-A1 | HETEROCYCLIC THR-B RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREFOR | THRB, THRA, TRHR | CYP3A4 1334/4885CHRM1 806/4885ALOX15 2304/4885 |
| US-11827596-B2 | Thyromimetics | TPO, TSHR, TTR | CYP3A4 918/4885CHRM1 8/4885ALOX15 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.