Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273967 | 1.00 | NCF1 (0.50) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL8393731 | 0.83 | NCF1 (0.52) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL20475558 | 0.81 | NCF1 (0.50) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL23283355 | 0.81 | NCF1 (0.50) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL14103941 | 0.80 | NCF1 (0.48) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL8039395 | 0.79 | NCF1 (0.47) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL22521545 | 0.79 | NCF1 (0.47) | NCF1METTL3NOS1NOS2MCHR1 | |
| SCHEMBL18572404 | 0.76 | PRMT5 (0.42) | METTL3MCHR1KMT2A | |
| SCHEMBL28070057 | 0.75 | NCF1 (0.55) | NCF1MAOBKMT2A | |
| SCHEMBL24635162 | 0.73 | NCF1 (0.49) | NCF1METTL3NOS1NOS2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279756-A | METTL3 modulators | 埃克森特治疗公司 | 2022-11-01 | — | — | CN | disclosed |