Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393731 | 0.74 | NCF1 (0.52) | NCF1MAOBMETTL3SMN1; SMN2NPC1 | |
| SCHEMBL20475558 | 0.73 | NCF1 (0.50) | NCF1MAOBMETTL3NOS1NOS2 | |
| SCHEMBL23283355 | 0.73 | NCF1 (0.50) | NCF1MAOBMETTL3NOS1NOS2 | |
| SCHEMBL23273967 | 0.73 | NCF1 (0.50) | NCF1MAOBMETTL3NOS1NOS2 | |
| SCHEMBL29970938 | 0.73 | NCF1 (0.50) | NCF1MAOBMETTL3NOS1NOS2 | |
| SCHEMBL5972991 | 0.72 | CYP1A2 (0.50) | KMT2A | |
| SCHEMBL14103941 | 0.71 | NCF1 (0.48) | NCF1METTL3NOS1NOS2 | |
| SCHEMBL24875987 | 0.71 | KDM4E (0.39) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL22521545 | 0.70 | NCF1 (0.47) | NCF1MAOBMETTL3NOS1NOS2 | |
| SCHEMBL8039395 | 0.70 | NCF1 (0.47) | NCF1METTL3SMN1; SMN2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220372040-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220372040-A1 | METTL3 MODULATORS | METTL3, METTL16, METTL14 | NCF1 2895/4885MAOB 2305/4885NUDT1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.