Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409524 | 1.00 | TSHR (0.48) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL13689692 | 0.86 | ALDH1A1 (0.48) | TSHRALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5023616 | 0.84 | THRB (0.56) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL9273411 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1HPGDCYP1A2CYP2A6 | |
| SCHEMBL31125356 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1HPGDCYP1A2CYP2A6 | |
| SCHEMBL1237641 | 0.78 | THRB (0.71) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL29593170 | 0.78 | THRB (0.71) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL19523016 | 0.78 | TYK2 (0.44) | TSHRALDH1A1KMT2AHPGDTRPA1 | |
| SCHEMBL30960116 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL23043313 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1HPGDLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279359-A | Novel thyromimetic agents | 速通医疗公司 | 2022-11-01 | — | — | CN | disclosed |