SCHEMBL29972292

SCHEMBL29972292

O=S(=O)(O)c1ccc2ccccc2c1-c1c(S(=O)(=O)O)ccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.53
MPL P40238 3/20 0.47
CTRC Q99895 2/20 0.47
WDR5 P61964 1/20 0.47
DNMT1 P26358 1/20 0.46
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 3/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
HIF1A Q16665 2/20 0.43
CES1 P23141 2/20 0.43
CYP1B1 Q16678 1/20 0.43
GPR84 Q9NQS5 1/20 0.42
TTR P02766 1/20 0.41
ERN1 O75460 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2785876 1.00 CTRB1 (0.53) CTRB1MPLCTRCWDR5DNMT1
Ammonia Solution, Strong SCHEMBL3630747 0.98 CTRB1 (0.51) CTRB1MPLCTRCWDR5DNMT1
SCHEMBL28929540 0.91 MPL (0.52) CTRB1MPLCTRCALDH1A1HSD17B10
SCHEMBL9507140 0.89 CTRB1 (0.48) CTRB1MPLCTRCWDR5DNMT1
SCHEMBL29740512 0.87 DNMT1 (0.47) CTRB1MPLCTRCWDR5DNMT1
Hydrochloric Acid SCHEMBL28180680 0.86 CTRB1 (0.49) CTRB1MPLCTRCWDR5DNMT1
SCHEMBL29002787 0.84 GPR84 (0.47) CTRB1MPLCTRCWDR5ALDH1A1
SCHEMBL28723636 0.84 CTRB1 (0.48) CTRB1MPLCTRCWDR5TDP1
SCHEMBL41541 0.83 CYP2D6 (0.53) CTRB1MPLCTRCALDH1A1HSD17B10
SCHEMBL8645212 0.82 CTRB1 (0.51) CTRB1MPLCTRCALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304520-A Polybasic sulfonic acid compound, intermediate and application thereof 上海科技大学 2022-11-08 CN disclosed