SCHEMBL17439396

SCHEMBL17439396

COc1ccc2c(c1)-c1ccccc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
NPC1 O15118 2/20 0.55
MAPK1 P28482 1/20 0.55
GAA P10253 1/20 0.55
ALOX12 P18054 1/20 0.55
PTPN1 P18031 2/20 0.54
AR P10275 1/20 0.54
TP53 P04637 2/20 0.54
MAP2K7 O14733 1/20 0.54
GMNN O75496 1/20 0.54
LMNA P02545 1/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2997273 0.96 PTPN1 (0.54) MAPTTDP1RAB9ASMN1; SMN2KDM4E
SCHEMBL4645032 0.96 PTPN1 (0.58) MAPTTDP1RAB9ASMN1; SMN2KDM4E
2-Methoxyanthraquinone SCHEMBL222927 0.94 PTPN1 (0.60) MAPTTDP1RAB9ASMN1; SMN2KDM4E
SCHEMBL23111380 0.92 PTPRC (0.59) MAPTTDP1RAB9ASMN1; SMN2KDM4E
SCHEMBL10885799 0.92 CA1 (0.53) MAPTRAB9AALDH1A1HPGDPTPN1
SCHEMBL7786812 0.92 CA1 (0.57) MAPTRAB9AALDH1A1HPGDPTPN1
SCHEMBL31669020 0.89 GPR3 (0.59) MAPTRAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL25693544 0.89 GPR3 (0.59) MAPTRAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL2993382 0.88 CA1 (0.53) MAPTRAB9AALDH1A1HPGDPTPN1
SCHEMBL7451901 0.87 CA1 (0.57) MAPTRAB9AALDH1A1HPGDPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113652705-B Method for synthesizing fluorenone through catalytic electrolysis of N-hydroxyphthalimide 北京工业大学 2022-07-22 CN disclosed
CN-113652705-A Method for synthesizing fluorenone by catalyzing and electrolyzing N-hydroxyphthalimide 北京工业大学 2021-11-16 CN disclosed
US-9880469-B2 Resins for underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-01-30 US disclosed
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-01-28 US disclosed
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-01-28 US disclosed
US-20160016872-A1 RESINS FOR UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160023978-A1 6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME SUN2, UACA, HNF4A MAPT 1162/4885TDP1 2987/4885RAB9A 1752/4885
US-20160016872-A1 RESINS FOR UNDERLAYERS AS3MT, TET2, MMAB MAPT 2843/4885TDP1 253/4885RAB9A 4749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.