Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | QPCT | Q16769 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525857 | 1.00 | TP53 (0.68) | TP53MAPK1MAPTQPCTLMNA | |
| SCHEMBL29973704 | 0.91 | TP53 (0.79) | TP53MAPK1MAPTQPCTALDH1A1 | |
| SCHEMBL1525818 | 0.91 | TP53 (0.79) | TP53MAPK1MAPTQPCTALDH1A1 | |
| SCHEMBL12964826 | 0.86 | MAPT (0.72) | TP53MAPK1MAPTQPCTLMNA | |
| SCHEMBL12964617 | 0.85 | MAPT (0.64) | TP53MAPK1MAPTQPCTLMNA | |
| SCHEMBL1525960 | 0.82 | ALDH1A1 (0.59) | TP53MAPK1LMNAALDH1A1MEN1 | |
| SCHEMBL1525994 | 0.81 | TP53 (0.59) | TP53MAPK1QPCTLMNAALDH1A1 | |
| SCHEMBL11010135 | 0.81 | MEN1 (0.69) | TP53MAPK1LMNAALDH1A1MEN1 | |
| SCHEMBL21637934 | 0.81 | MAPT (1.00) | MAPTQPCTLMNARAB9AALDH1A1 | |
| SCHEMBL1526009 | 0.80 | TP53 (0.61) | TP53MAPK1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536691-B1 | CHEMICAL MOLECULES THAT INHIBIT THE SPLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES | CENTRE NAT RECH SCIENT (FR) | 2022-10-05 | — | — | EP | disclosed |