Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | QPCT | Q16769 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525818 | 1.00 | TP53 (0.79) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL1525857 | 0.91 | TP53 (0.68) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL29973069 | 0.91 | TP53 (0.68) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL1526009 | 0.87 | TP53 (0.61) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL1525994 | 0.86 | TP53 (0.59) | TP53MAPK1ALDH1A1HSD17B10HPGD | |
| SCHEMBL11015706 | 0.86 | MAPK1 (0.73) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL12767077 | 0.84 | ALDH1A1 (0.89) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL1525787 | 0.84 | TP53 (0.70) | TP53MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL11010135 | 0.84 | MEN1 (0.69) | TP53MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1525960 | 0.84 | ALDH1A1 (0.59) | TP53MAPK1ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536691-B1 | CHEMICAL MOLECULES THAT INHIBIT THE SPLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES | CENTRE NAT RECH SCIENT (FR) | 2022-10-05 | — | — | EP | disclosed |