Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010881 | 0.88 | LDHA (0.45) | CHRM4AOC3F10JAK2JAK1 | |
| SCHEMBL31614778 | 0.88 | MGLL (0.44) | CHRM4CHRM2PIK3CAKMT2AMAPK1 | |
| SCHEMBL30455908 | 0.86 | CHRM4 (0.57) | CHRM4CHRM2ACACBKMT2A | |
| SCHEMBL29973458 | 0.84 | CHRM4 (0.57) | CHRM4CHRM2ACACB | |
| SCHEMBL21847675 | 0.84 | CHRM4 (0.57) | CHRM4CHRM2JAK2JAK1TYK2 | |
| SCHEMBL21847696 | 0.84 | CHRM4 (0.57) | CHRM4CHRM2ACACBKMT2ACYP1A2 | |
| SCHEMBL31647857 | 0.84 | CHRM4 (0.49) | CHRM4F10KMT2A | |
| SCHEMBL20594817 | 0.84 | CHRM4 (0.58) | CHRM4CHRM2F10TMEM97CYP1A2 | |
| SCHEMBL29839994 | 0.84 | CHRM4 (0.58) | CHRM4CHRM2F10TMEM97CYP1A2 | |
| SCHEMBL21847855 | 0.83 | CHRM4 (0.60) | CHRM4CHRM2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122809-A1 | M4 POSITIVE ALLOSTERIC MODULATORS | ACADIA PHARMACEUTICALS INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| EP-3642202-B1 | DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2022-11-02 | — | — | EP | disclosed |