Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587088 | 0.80 | IRAK4 (0.41) | DYRK1A | |
| SCHEMBL29973049 | 0.79 | DHFR (0.42) | KMT2APIK3CA | |
| SCHEMBL30505055 | 0.74 | NPC1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL27865729 | 0.73 | MAPK1 (0.54) | JAK3 | |
| SCHEMBL29972663 | 0.72 | PDPK1 (0.40) | ALDH1A1KMT2APKMPDPK1CLK4 | |
| SCHEMBL29972741 | 0.72 | GAA (0.35) | KDM4EALDH1A1MAPTGAAKMT2A | |
| SCHEMBL4235899 | 0.68 | MEN1 (0.30) | KMT2ALMNA | |
| SCHEMBL6049514 | 0.66 | KDM4E (0.52) | KDM4EALDH1A1MAPTGAADYRK1A | |
| SCHEMBL27698162 | 0.65 | — | — | |
| SCHEMBL23030123 | 0.64 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115381832-A | Treatment of cancer | 深圳明赛瑞霖药业有限公司 | 2022-11-25 | — | — | CN | disclosed |