Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.63 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.54 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | CTSH | P09668 | 1/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500468 | 0.92 | C5AR1 (0.59) | TACR2CXCR4C5AR1DPP3CTSL | |
| SCHEMBL29973278 | 0.90 | TACR2 (0.66) | TACR2CXCL8DPP3OPRM1TACR1 | |
| SCHEMBL29520254 | 0.89 | KISS1R (0.62) | TACR2CXCR4DPP3CTSLCTSS | |
| SCHEMBL6041194 | 0.89 | CXCR4 (0.61) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL6041189 | 0.89 | CXCR4 (0.61) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL30288110 | 0.88 | KISS1R (0.61) | CXCR4C5AR1DPP3KISS1R | |
| SCHEMBL31452905 | 0.87 | CXCR4 (0.62) | CXCR4C5AR1KISS1ROPRM1 | |
| SCHEMBL29476405 | 0.86 | KISS1R (0.55) | TACR2CXCR4C5AR1DPP3CTSL | |
| SCHEMBL29476509 | 0.86 | KISS1R (0.55) | TACR2CXCR4C5AR1DPP3CTSL | |
| SCHEMBL30565410 | 0.86 | C5AR1 (0.56) | CXCR4C5AR1DPP3CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |