Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578075 | 1.00 | MEN1 (0.33) | MEN1HTTKMT2ARORCSLC6A3 | |
| SCHEMBL23578490 | 0.87 | KMT2A (0.37) | MEN1HTTKMT2ARORCSLC6A3 | |
| SCHEMBL23588153 | 0.87 | MEN1 (0.37) | MEN1HTTKMT2ALMNAMAPT | |
| SCHEMBL23578140 | 0.86 | SLC6A3 (0.34) | MEN1HTTKMT2ARORCSLC6A3 | |
| SCHEMBL29844081 | 0.86 | SLC6A3 (0.34) | MEN1HTTKMT2ARORCSLC6A3 | |
| SCHEMBL23578539 | 0.85 | CCR5 (0.36) | MEN1HTTKMT2AMAPT | |
| SCHEMBL25801965 | 0.85 | MEN1 (0.32) | MEN1HTTKMT2A | |
| SCHEMBL25801800 | 0.84 | KMT2A (0.46) | MEN1HTTKMT2ASLC6A3LMNA | |
| SCHEMBL23588062 | 0.83 | KMT2A (0.40) | MEN1HTTKMT2ALMNAMAPT | |
| SCHEMBL23588264 | 0.83 | MEN1 (0.36) | MEN1HTTKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |