SCHEMBL29973407

SCHEMBL29973407

Cc1ccc(Cl)c2onc(OCCN)c12

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 2/20 0.35
CYP17A1 P05093 3/20 0.33
PARP1 P09874 1/20 0.32
PARP3 Q9Y6F1 1/20 0.32
KMT2A Q03164 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
SENP2 Q9HC62 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6995997 0.99 CHEK1 (0.34) CHEK1CYP17A1PARP1PARP3KMT2A
SCHEMBL29416851 0.88 CYP17A1 (0.35) CHEK1CYP17A1KMT2A
SCHEMBL6987236 0.88 CYP17A1 (0.35) CHEK1CYP17A1KMT2A
Hydrochloric Acid SCHEMBL6992724 0.86 KDM4E (0.35) CHEK1CYP17A1SMN1; SMN2
Hydrochloric Acid SCHEMBL8521788 0.84 CYP17A1 (0.32) CYP17A1KMT2AMEN1HTT
Hydrochloric Acid SCHEMBL6988376 0.80 CHEK1 (0.34) CHEK1
SCHEMBL6989532 0.79 IDO1 (0.33) CHEK1CYP17A1
Hydrochloric Acid SCHEMBL6989390 0.78 IDO1 (0.33) CHEK1CYP17A1
SCHEMBL6999378 0.78 CHEK1 (0.34) CHEK1KMT2AMEN1HTT
Hydrochloric Acid SCHEMBL6994162 0.77 CHEK1 (0.34) CHEK1KMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115394357-A Site combination for judging sample pairing or pollution and screening method and application thereof 杭州链康医学检验实验室有限公司 2022-11-25 CN disclosed