Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081392 | 0.82 | HRH3 (0.39) | OPRD1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL486492 | 0.82 | — | — | |
| SCHEMBL87801 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL1934293 | 0.80 | HRH3 (0.38) | OPRD1MAPTALDH1A1SMN1; SMN2KDM4E | |
| Iodide SCHEMBL28911088 | 0.80 | SMN1; SMN2 (0.38) | OPRD1MAPTALDH1A1SMN1; SMN2KDM4E | |
| Bromide SCHEMBL1471663 | 0.80 | HRH3 (0.38) | OPRD1MAPTALDH1A1KDM4EMEN1 | |
| Bromide SCHEMBL10332289 | 0.80 | HRH3 (0.38) | OPRD1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL88222 | 0.80 | — | — | |
| SCHEMBL1489209 | 0.80 | — | — | |
| Nitric Acid SCHEMBL10591820 | 0.79 | KDM4E (0.38) | OPRD1ALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115064786-A | Electrolyte, zinc ion battery, and preparation method and application of zinc ion battery | 华南师范大学 | 2022-09-16 | — | — | CN | disclosed |