Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1934293

C=CCN1CCCCC1.N

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.38
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
MAPT P10636 3/20 0.35
ADRA2A P08913 2/20 0.35
ADRA2B P18089 2/20 0.35
ADRA2C P18825 2/20 0.35
ADRA1A P35348 2/20 0.35
LMNA P02545 1/20 0.35
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
OPRK1 P41145 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
OPRD1 P41143 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8854910 0.97
SCHEMBL1081392 0.97 HRH3 (0.39) HRH3CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL87801 0.97
SCHEMBL486492 0.97
Bromide SCHEMBL10332289 0.94 HRH3 (0.38) HRH3CHRNB2CHRNB4CHRNA3CHRNA4
Bromide SCHEMBL1471663 0.94 HRH3 (0.38) HRH3CHRNB2CHRNB4CHRNA3CHRNA4
Iodide SCHEMBL28911088 0.94 SMN1; SMN2 (0.38) HRH3CHRNB2CHRNB4CHRNA3CHRNA4
Hydrochloric Acid SCHEMBL28067318 0.94 SIGMAR1 (0.39) HRH3CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL1489209 0.94
SCHEMBL88222 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101027311-A Resorcinol carbonate-based phosphate compounds as flame retardants INDSPEC CHEMICAL CORP (US) 2007-08-29 CN claimed
EP-2503878-B1 DENDRITIC POLYUREA FOR SOLUBILIZING ACTIVE SUBSTANCES OF LOW SOLUBILITY BASF SE (DE) 2015-01-28 EP disclosed
US-8936902-B2 Positive-working imageable elements and method of use EASTMAN KODAK COMPANY (US) 2015-01-20 US disclosed
US-20140341822-A1 Associative Thickeners Based on Hyperbranched Polymers BASF SE (DE) 2014-11-20 US disclosed
EP-2739664-A1 ASSOCIATIVE THICKENERS BASED ON HYPERBRANCHED POLYMERS BASF SE (DE) 2014-06-11 EP disclosed
US-8728504-B2 Process for solubilizing hydrophobic active ingredients in aqueous medium BASF SE (DE) 2014-05-20 US disclosed
WO-2013020820-A1 ASSOCIATIVE THICKENERS BASED ON HYPERBRANCHED POLYMERS BASF SE (DE) 2013-02-14 WO disclosed
EP-2531548-A1 METHOD FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AN AQUEOUS SOLUTION BASF SE (DE) 2012-12-12 EP disclosed
EP-2503878-A1 DENDRITIC POLYUREA FOR SOLUBILIZING ACTIVE SUBSTANCES OF LOW SOLUBILITY BASF SE (DE) 2012-10-03 EP disclosed
WO-2011095449-A1 METHOD FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AN AQUEOUS SOLUTION BASF SE (DE) 2011-08-11 WO disclosed
EP-1590326-A2 SUBSTITUTED ALKYL AMIDO PIPERIDINES H. Lundbeck A/S (DK) 2005-11-02 EP disclosed
US-20050222360-A1 Method for the production of highly functional, highly branched polyureas BASF AKTIENGESELLSCHAFT (DE) 2005-10-06 US disclosed
US-20040186103-A1 Substituted alkyl amido piperidines SYNAPTIC PHARMACEUTICAL CORPORATION 2004-09-23 US disclosed
WO-2004064764-A2 SUBSTITUTED ALKYL AMIDO PIPERIDINES H. LUNDBECK A/S (DK) 2004-08-05 WO disclosed
US-5684122-A IMIDIZED MALEIC ANHYDRIDE-OLEFIN COPOLYMER, PHYLLOSILICATE TOSOH CORPORATION (JP) 1997-11-04 US disclosed
EP-0156210-B1 CURABLE RESIN COMPOSITIONS BASED ON TERTIARY AMINO GROUP-CONTAINING VINYL POLYMERS DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-06-13 EP disclosed
US-4670521-A Process for producing tertiary amino group-containing vinyl polymers and curable resin compositions based on these polymers DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-06-02 US disclosed
US-4634736-A PAINTS DAINIPPON INK & CHEMICALS (JP) 1987-01-06 US disclosed
EP-0156210-A2 Curable resin compositions based on tertiary amino group-containing vinyl polymers DAINIPPON INK AND CHEMICALS, INC. (JP) 1985-10-02 EP disclosed
US-4446281-A Modified cis-1,4-polyisoprene rubber, a process for manufacturing the same, and a composition containing the same KURARAY CO., LTD. (JP) 1984-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140341822-A1 Associative Thickeners Based on Hyperbranched Polymers DSG1, TAF11, UROD HRH3 1843/4885CHRNB2 3062/4885CHRNB4 2804/4885
US-20040186103-A1 Substituted alkyl amido piperidines MCHR1, MCHR2, MC1R HRH3 129/4885CHRNB2 358/4885CHRNB4 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.