Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653224 | 1.00 | GPR55 (0.57) | GPR55ALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL10055036 | 0.84 | GPR55 (0.60) | GPR55ALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL7231916 | 0.83 | FABP1 (0.58) | ALDH1A1KDM4EHPGDHDAC1FYN | |
| SCHEMBL22191375 | 0.80 | GPR55 (0.57) | GPR55ALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL14950724 | 0.80 | GPR55 (0.54) | GPR55ALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL23609081 | 0.80 | ALDH1A1 (0.62) | GPR55ALDH1A1KDM4EHPGDCXCR1 | |
| SCHEMBL30592887 | 0.80 | NPC1 (0.61) | HPGDHDAC1FYNMEN1KMT2A | |
| SCHEMBL29996542 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ECYP2D6CYP2C19CYP3A4 | |
| SCHEMBL10055037 | 0.77 | FYN (0.56) | GPR55ALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL22602024 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDCXCR4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |