Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | RAF1 | P04049 | 3/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.44 |
| ▸ | AKT2 | P31751 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997384 | 1.00 | IKBKB (0.44) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL3636699 | 0.91 | MAPK1 (0.48) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL3636696 | 0.91 | MAPK1 (0.48) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL3000164 | 0.80 | IKBKB (0.44) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL3000161 | 0.80 | IKBKB (0.44) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 | |
| SCHEMBL3001641 | 0.78 | PIK3CD (0.41) | MAPK1AKT1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3001639 | 0.78 | PIK3CD (0.41) | MAPK1AKT1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2997704 | 0.75 | KMT2A (0.38) | MAPK1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2997702 | 0.75 | KMT2A (0.38) | MAPK1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL3005242 | 0.75 | MAPT (0.39) | IKBKBPRKAG1PRKAA1NEK1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2010-07-29 | — | — | US | claimed |
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | HSF1, HSPA4, HSPA5 | IKBKB 1256/4885PRKAG1 1864/4885PRKAA1 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.