Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997704 | 1.00 | KMT2A (0.38) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL2997705 | 0.89 | ALDH1A1 (0.49) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL2997703 | 0.89 | ALDH1A1 (0.49) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL3006044 | 0.78 | ACHE (0.53) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL3006047 | 0.78 | ACHE (0.53) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL2997382 | 0.75 | IKBKB (0.44) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL2997384 | 0.75 | IKBKB (0.44) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL3006677 | 0.72 | LMNA (0.51) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL3006675 | 0.72 | LMNA (0.51) | KMT2AMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL3005164 | 0.72 | MAPT (0.50) | KMT2AMAPTMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190824-A1 | Novel Substituted Piperidones as HSP Inducers | HSF1, HSPA4, HSPA5 | KMT2A 4596/4885MAPT 40/4885MAPK1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.