Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925375 | 1.00 | PDCD1 (0.43) | PDCD1CD274GRM5CYP1A2GPR35 | |
| SCHEMBL25616220 | 0.93 | PDCD1 (0.41) | PDCD1CD274GRM5CYP1A2GPR35 | |
| SCHEMBL26090799 | 0.88 | CYP11B2 (0.41) | CYP1A2FFAR1FFAR4GAAMAP2K1 | |
| SCHEMBL29150011 | 0.86 | PDCD1 (0.39) | PDCD1CD274GPR35FFAR1FFAR4 | |
| SCHEMBL30154459 | 0.83 | PDCD1 (0.40) | PDCD1CD274GRM5CYP1A2GPR35 | |
| SCHEMBL23832208 | 0.83 | PDCD1 (0.40) | PDCD1CD274GRM5CYP1A2GPR35 | |
| SCHEMBL23832241 | 0.82 | TRPV4 (0.42) | PDCD1CD274GPR35GAANPSR1 | |
| SCHEMBL30154458 | 0.82 | TRPV4 (0.42) | PDCD1CD274GPR35GAANPSR1 | |
| SCHEMBL23832291 | 0.82 | CYP11B2 (0.39) | CYP1A2GAAMAP2K1SMN1; SMN2CYP11B1 | |
| SCHEMBL30154457 | 0.82 | CYP11B2 (0.39) | CYP1A2GAAMAP2K1SMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397826-A | Substituted {1,2,4, } triazolo {1,5-a } pyrimidine compounds and their use for the stabilization of microtubules | 宾夕法尼亚大学理事会 | 2022-11-25 | — | — | CN | disclosed |