Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525957 | 1.00 | SOD1 (0.52) | SOD1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL1499660 | 0.86 | KDR (0.53) | SOD1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL1499525 | 0.84 | MEN1 (0.50) | SOD1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL1499625 | 0.80 | MAPT (0.66) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL29973775 | 0.80 | KDR (0.64) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL1499580 | 0.80 | KDR (0.64) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL29973464 | 0.80 | MAPT (0.66) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL1525996 | 0.78 | MEN1 (0.48) | MEN1KMT2AKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL1525990 | 0.75 | MEN1 (0.50) | MEN1KMT2AKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL11427078 | 0.74 | SMN1; SMN2 (0.56) | MEN1KMT2AKDM4EL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536691-B1 | CHEMICAL MOLECULES THAT INHIBIT THE SPLICING MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICING ANOMALIES | CENTRE NAT RECH SCIENT (FR) | 2022-10-05 | — | — | EP | disclosed |