Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960656 | 1.00 | LMNA (0.55) | LMNAGID4CYP19A1MAOBABCG2 | |
| SCHEMBL22882748 | 0.89 | FFAR1 (0.49) | LMNAGID4CYP19A1MAOBABCG2 | |
| SCHEMBL4360502 | 0.84 | ESR1 (0.63) | LMNAGID4CYP19A1ABCG2ABCB1 | |
| SCHEMBL16160573 | 0.84 | ESR2 (0.63) | LMNACYP19A1FFAR1 | |
| SCHEMBL11050225 | 0.84 | MAOB (0.58) | GID4CYP19A1MAOBABCG2ABCB1 | |
| SCHEMBL29974186 | 0.84 | MAOB (0.58) | GID4CYP19A1MAOBABCG2ABCB1 | |
| Flavane SCHEMBL27534414 | 0.82 | KDM4E (0.47) | CYP19A1MAOBABCG2ABCB1AR | |
| SCHEMBL11053487 | 0.82 | ABCB1 (0.61) | CYP19A1MAOBABCG2ABCB1AR | |
| SCHEMBL27221220 | 0.82 | CYP19A1 (0.58) | CYP19A1MAOBABCG2ABCB1AR | |
| SCHEMBL9513009 | 0.81 | SRC (0.40) | LMNASLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022202961-A1 | METHOD FOR PRODUCING DEMETHYLATED COMPOUND | 株式会社ダイセル | 2022-09-29 | — | — | WO | disclosed |