Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | SLC8A1 | P32418 | 10/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439502 | 0.88 | LMNA (0.39) | LMNAESR1ESR2SLC8A1 | |
| SCHEMBL2960656 | 0.81 | LMNA (0.55) | LMNASLC8A1 | |
| SCHEMBL29974296 | 0.81 | LMNA (0.55) | LMNASLC8A1 | |
| Flavane SCHEMBL10624050 | 0.80 | ESR1 (0.48) | ESR1ESR2SLC8A1 | |
| Flavane SCHEMBL27764824 | 0.79 | ESR1 (0.47) | ESR1ESR2SLC8A1 | |
| SCHEMBL1542441 | 0.76 | ESR1 (0.57) | ESR1ESR2SLC8A1 | |
| SCHEMBL29974120 | 0.76 | ESR1 (0.57) | ESR1ESR2SLC8A1 | |
| Flavane SCHEMBL26661841 | 0.75 | ESR1 (0.54) | ESR1ESR2SLC8A1 | |
| Flavane SCHEMBL123287 | 0.73 | ESR1 (0.51) | ESR1ESR2SLC8A1 | |
| Flavane SCHEMBL14394530 | 0.73 | ESR1 (0.51) | ESR1ESR2SLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274425-B1 | Pyruvate oxidase, its preparation and use | ASAHI CHEMICAL IND (JP) | 1993-12-15 | — | — | EP | claimed |
| EP-0274425-A2 | Pyruvate oxidase, its preparation and use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-07-13 | — | — | EP | claimed |
| EP-0274425-B1 | Pyruvate oxidase, its preparation and use | ASAHI CHEMICAL IND (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0274425-A2 | Pyruvate oxidase, its preparation and use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-07-13 | — | — | EP | disclosed |