Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.52 |
| ▸ | INSR | P06213 | 5/20 | 0.47 |
| ▸ | IGF1R | P08069 | 5/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083977 | 1.00 | EGFR (0.52) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29084073 | 0.86 | INSR (0.54) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29084091 | 0.86 | EGFR (0.53) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29084051 | 0.85 | EGFR (0.56) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29084102 | 0.81 | EGFR (0.55) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29083952 | 0.80 | PLK1 (0.52) | EGFRPLK1 | |
| SCHEMBL29084086 | 0.80 | EGFR (0.53) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29083964 | 0.80 | EGFR (0.53) | EGFRINSRIGF1RALK | |
| SCHEMBL29084066 | 0.80 | EGFR (0.55) | EGFRINSRIGF1RALKPLK1 | |
| SCHEMBL29083960 | 0.80 | EGFR (0.55) | EGFRINSRIGF1RALKPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | claimed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | disclosed |