Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.64 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 5/20 | 0.48 |
| ▸ | IGF1R | P08069 | 5/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084096 | 0.90 | EGFR (0.71) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL29083963 | 0.88 | EGFR (0.65) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL29084045 | 0.86 | EGFR (0.67) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL29084036 | 0.86 | EGFR (0.65) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL27091519 | 0.86 | EGFR (0.67) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL29083941 | 0.84 | EGFR (0.55) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL23442003 | 0.84 | EGFR (0.61) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL29974926 | 0.84 | EGFR (0.65) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL29974578 | 0.83 | EGFR (0.62) | EGFRBTK | |
| SCHEMBL30860381 | 0.83 | EGFR (0.60) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |