Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 17/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 17/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 17/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410689 | 0.88 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL25043423 | 0.86 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL27353304 | 0.80 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL28958052 | 0.74 | PTGS2 (0.54) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL4587383 | 0.74 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL1387655 | 0.73 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL23411206 | 0.72 | GFER (0.42) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL23410267 | 0.71 | HTT (0.46) | — | |
| SCHEMBL23410397 | 0.71 | PTGS2 (0.55) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL28878620 | 0.71 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151256-A | Novel compounds for the treatment of diseases associated with DUX expression | FACIO知识产权有限公司 | 2022-10-04 | — | — | CN | disclosed |