Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569154 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL29569227 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL30087026 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL15063036 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL31127473 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL190685 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL25966 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL4850502 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL29418187 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL5692997 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11926617-B2 | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-20220315562-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315562-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | CFD, TFPI, CFH | ALDH1A1 2717/4885HSD17B10 1764/4885HIF1A 1666/4885 |
| US-11926617-B2 | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders | CFD, TFPI, CFH | ALDH1A1 2717/4885HSD17B10 1764/4885HIF1A 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.