Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 7/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155912 | 1.00 | HPGDS (0.41) | HPGDSSCN9AHSD11B1SYKMKNK1 | |
| SCHEMBL29326100 | 0.71 | HSD11B1 (0.37) | HPGDSSCN9AHSD11B1MKNK1MKNK2 | |
| SCHEMBL31197278 | 0.70 | CDK7 (0.43) | CRBN | |
| SCHEMBL16000542 | 0.69 | SCN9A (0.38) | HPGDSSCN9AHSD11B1MKNK1MKNK2 | |
| SCHEMBL29325902 | 0.69 | SCN9A (0.33) | HPGDSSCN9AHSD11B1SYKMKNK1 | |
| SCHEMBL29325904 | 0.69 | SCN9A (0.33) | HPGDSSCN9AHSD11B1SYKMKNK1 | |
| SCHEMBL29326076 | 0.67 | IDH1 (0.47) | HSD11B1MKNK1MKNK2 | |
| SCHEMBL29326073 | 0.67 | IDH1 (0.44) | HSD11B1SYKMKNK1MKNK2 | |
| SCHEMBL29326072 | 0.66 | HPGDS (0.41) | HPGDSCD274 | |
| SCHEMBL29974713 | 0.66 | HPGDS (0.41) | HPGDSCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222626-A | Substituted triazine compounds | 安斯泰来制药株式会社 | 2023-12-12 | — | — | CN | disclosed |
| WO-2022230912-A1 | SUBSTITUTED TRIAZINE COMPOUND | アステラス製薬株式会社 | 2022-11-03 | — | — | WO | disclosed |