SCHEMBL29975387

SCHEMBL29975387

CCO[Si](C(C)(C)CC)(C(C)(C)CC)C(C)(C)CC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2399265 0.77 TSHR (0.32) TSHRTDP1ALDH1A1
SCHEMBL5002952 0.77 TSHR (0.32) TSHRTDP1ALDH1A1
SCHEMBL705102 0.75
SCHEMBL301818 0.74 TSHR (0.30) TSHRTDP1
SCHEMBL9243242 0.74 TSHR (0.30) TSHRTDP1
SCHEMBL301382 0.72
SCHEMBL8852530 0.72
SCHEMBL301675 0.69
SCHEMBL8852332 0.69
SCHEMBL15184962 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022213043-A1 METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE TOKYO OHKA KOGYO CO., LTD. (JP) 2022-10-06 WO disclosed