Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | IL1B | P01584 | 8/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696179 | 0.99 | NLRP3 (0.54) | NLRP3KCNH2IL1BTNFGABBR2 | |
| SCHEMBL29326630 | 0.92 | NLRP3 (0.52) | NLRP3KCNH2IL1BTNFGABBR2 | |
| SCHEMBL29326441 | 0.91 | NLRP3 (0.53) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30375405 | 0.90 | IL1B (0.52) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL26092873 | 0.90 | IL1B (0.52) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30684741 | 0.90 | IL1B (0.52) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL27182193 | 0.90 | IL1B (0.52) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL29155909 | 0.89 | IL1B (0.53) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30054441 | 0.89 | IL1B (0.53) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL30684869 | 0.89 | IL1B (0.53) | NLRP3KCNH2IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022230912-A1 | SUBSTITUTED TRIAZINE COMPOUND | アステラス製薬株式会社 | 2022-11-03 | — | — | WO | disclosed |