Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806087 | 1.00 | DRD2 (0.52) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL29976523 | 0.94 | DRD2 (0.46) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL19806083 | 0.94 | DRD2 (0.46) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL3211659 | 0.85 | DRD2 (0.53) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL19806086 | 0.84 | POLB (0.52) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL3211645 | 0.84 | DRD2 (0.52) | DRD2MAOBMAOACA2CA12 | |
| Hydrochloric Acid SCHEMBL5708176 | 0.83 | DRD2 (0.51) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL22916119 | 0.83 | DRD2 (0.51) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL22916143 | 0.83 | DRD2 (0.51) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL16774310 | 0.81 | DRD2 (0.50) | DRD2MAOBMAOACA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |