Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211659 | 0.85 | DRD2 (0.53) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL19806086 | 0.84 | POLB (0.52) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL29975770 | 0.84 | DRD2 (0.52) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL19806087 | 0.84 | DRD2 (0.52) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL22916096 | 0.83 | ALDH1A1 (0.69) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL22916119 | 0.83 | DRD2 (0.51) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL22916143 | 0.83 | DRD2 (0.51) | DRD2MAOBMAOACA2CA12 | |
| Hydrochloric Acid SCHEMBL5708176 | 0.83 | DRD2 (0.51) | DRD2MAOBMAOACA2CA12 | |
| SCHEMBL1929081 | 0.81 | CA2 (0.43) | DRD2CA2ALDH1A1PPARGPPARD | |
| SCHEMBL6660288 | 0.81 | ATM (0.68) | DRD2MAOBMAOACA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415272-B2 | Quinoline derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100056570-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056570-A1 | FUNGICIDES | CYP21A2, CYP51A1, CYP4X1 | DRD2 2140/4885MAOB 731/4885MAOA 496/4885 |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | DRD2 984/4885MAOB 956/4885MAOA 623/4885 |
| US-20100280068-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A1, CYP3A7, CYP1A2 | DRD2 955/4885MAOB 1003/4885MAOA 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.