Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985661 | 1.00 | BRD4 (0.35) | BRD4HTR2AHTR2CSLC6A4GNRHR | |
| SCHEMBL19806101 | 0.93 | PDE2A (0.33) | BRD4 | |
| SCHEMBL29976568 | 0.93 | PDE2A (0.33) | BRD4 | |
| SCHEMBL19805938 | 0.87 | BRD4 (0.34) | BRD4HTR2AHTR2CSLC6A4GNRHR | |
| SCHEMBL20985727 | 0.86 | BRD4 (0.36) | BRD4HTR2AHTR2CSLC6A4GNRHR | |
| SCHEMBL29976175 | 0.83 | MAPK14 (0.32) | GNRHR | |
| SCHEMBL19805939 | 0.83 | MAPK14 (0.32) | GNRHR | |
| SCHEMBL23503847 | 0.82 | BRD4 (0.36) | BRD4HTR2AHTR2CSLC6A4GNRHR | |
| SCHEMBL19806095 | 0.81 | SDHB (0.35) | — | |
| SCHEMBL29975734 | 0.81 | SDHB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | BRD4 1441/4885HTR2A 3517/4885HTR2C 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.