Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805972 | 1.00 | KMT2A (0.49) | KMT2AKDM4EALDH1A1NOTUMPOLB | |
| SCHEMBL15904214 | 0.81 | ADORA2A (0.50) | KMT2AKDM4EALDH1A1MEN1GAA | |
| SCHEMBL30487823 | 0.81 | ADORA2A (0.50) | KMT2AKDM4EALDH1A1MEN1GAA | |
| SCHEMBL6140559 | 0.77 | KMT2A (0.58) | KMT2AKDM4EPOLBMEN1SMN1; SMN2 | |
| SCHEMBL20416864 | 0.76 | KDM4E (0.46) | KMT2AKDM4EALDH1A1NOTUMMEN1 | |
| SCHEMBL24253941 | 0.75 | KDM4E (0.42) | KMT2AKDM4EALDH1A1NOTUMMEN1 | |
| SCHEMBL28326781 | 0.74 | ALDH1A1 (0.48) | KMT2AKDM4EALDH1A1NOTUMMEN1 | |
| SCHEMBL19687410 | 0.73 | KDM4E (0.40) | KMT2AKDM4EALDH1A1NOTUMMEN1 | |
| SCHEMBL20985734 | 0.73 | MEN1 (0.40) | KMT2AKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL6141180 | 0.72 | KMT2A (0.52) | KMT2AKDM4EALDH1A1NOTUMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |