SCHEMBL2997631

SCHEMBL2997631

O=C(Nc1ccccc1)c1ccc(CCl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.65
HDAC2 Q92769 1/20 0.62
HDAC8 Q9BY41 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
TRPV1 Q8NER1 1/20 0.62
RXFP1 Q9HBX9 1/20 0.62
HIF1A Q16665 1/20 0.58
EPAS1 Q99814 1/20 0.58
NR1H4 Q96RI1 1/20 0.58
KDM4E B2RXH2 2/20 0.58
POLB P06746 2/20 0.58
SIRT1 Q96EB6 1/20 0.58
PTPN11 Q06124 1/20 0.56
HPGD P15428 2/20 0.56
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11852178 0.93 PTPN1 (0.65) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL21674204 0.91 MEN1 (0.57) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL2021051 0.91 MEN1 (0.57) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL20697672 0.86 HIF1A (0.58) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL12440844 0.86 MEN1 (0.52) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL12440876 0.86 NR1H4 (0.62) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL1315526 0.84 PTPN1 (0.87) PTPN1HDAC2HDAC8HDAC6NPC1
SCHEMBL20548351 0.84 KMT2A (0.61) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL2642119 0.84 PTPN1 (0.67) PTPN1HDAC2HDAC8HDAC6NPC1
SCHEMBL2642122 0.84 PTPN1 (0.67) PTPN1HDAC2HDAC8HDAC6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109305949-B Monomer, polymer, compensation film, optical film and display device 三星电子株式会社 2023-08-15 CN disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 US disclosed
EP-3438156-B1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-04-22 EP disclosed
EP-3398970-B1 A METHOD OF SYNTHESIZING CELLULOSE CARBONATE AGENCY SCIENCE TECH & RES (SG) 2020-02-12 EP disclosed
EP-1179341-B1 REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES TEIJIN LTD (JP) 2005-11-09 EP disclosed
EP-1553085-A1 Cyclic amine derivatives and their use as drugs TEIJIN LIMITED (JP) 2005-07-13 EP disclosed
CN-1639116-A Phenolic compound and recording material using the same NIPPON SODA CO (JP) 2005-07-13 CN disclosed
EP-1535909-A2 Cyclic amine derivatives and their use as drugs TEIJIN LIMITED (JP) 2005-06-01 EP disclosed
US-20050096222-A1 For use in recording materials using a color developing dye, such as thermal sensitive recording material and pressure sensitive copying material, storage stability NIPPON SODA CO., LTD. (JP) 2005-05-05 US disclosed
CN-1384743-A Remedies or preventives for diseases in association with chemokines TEIJIN LTD (JP) 2002-12-11 CN disclosed
US-6451842-B1 Cyclic amine derivatives and their use as drugs DUPONT PHARMACEUTICALS COMPANY 2002-09-17 US disclosed
US-6410566-B1 ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS TEIJIN LIMITED (JP) 2002-06-25 US disclosed
US-6362177-B1 INHIBITION OF CHEMOKINE BINDING TEIJIN LIMITED (JP) 2002-03-26 US disclosed
EP-1179341-A1 REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES TEIJIN LIMITED (JP) 2002-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE PYM1, PADI1, COL1A1 PTPN1 285/4885HDAC2 4834/4885HDAC8 4875/4885
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device PYM1, PADI1, COL1A1 PTPN1 285/4885HDAC2 4834/4885HDAC8 4875/4885
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device RAP1A, PYM1, COL1A1 PTPN1 115/4885HDAC2 4786/4885HDAC8 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.