Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676880 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL27278065 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL506591 | 0.84 | NPC1 (0.49) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL3819546 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL9921443 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL6396893 | 0.82 | CYP2A6 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL13610284 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL2357662 | 0.82 | HSD17B10 (0.50) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL2620993 | 0.82 | NPC1 (0.47) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 | |
| SCHEMBL27281640 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TRPM5FFAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638436-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-10-29 | — | — | EP | disclosed |
| CN-118047780-A | Quinazoline heterocyclic compound and anti-infection and anti-tumor application thereof | 中国医学科学院药物研究所 | 2024-05-17 | — | — | CN | disclosed |
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |