Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806100 | 1.00 | POLB (0.42) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL254039 | 0.86 | POLB (0.44) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL5750658 | 0.84 | POLB (0.45) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL19805997 | 0.80 | HTT (0.43) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL62021 | 0.79 | POLB (0.53) | POLBKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL113146 | 0.78 | HRH4 (0.35) | SMN1; SMN2 | |
| SCHEMBL30809049 | 0.78 | HRH4 (0.35) | SMN1; SMN2 | |
| SCHEMBL31543344 | 0.76 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL30808934 | 0.74 | IDH1 (0.30) | — | |
| SCHEMBL19024133 | 0.74 | IDH1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |