Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902046 | 0.85 | POLB (0.47) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL29368005 | 0.84 | KMT2A (0.49) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL19805989 | 0.84 | POLB (0.46) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL12105468 | 0.84 | POLB (0.46) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL191585 | 0.84 | KMT2A (0.49) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL3110403 | 0.84 | KMT2A (0.51) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL4058565 | 0.84 | POLB (0.46) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11426179 | 0.82 | KMT2A (0.47) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10845926 | 0.82 | POLB (0.49) | POLBKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL5750658 | 0.82 | POLB (0.45) | POLBKMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390656-B | Compound and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2025-04-08 | — | — | CN | claimed |
| CN-119390656-A | Compound and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2025-02-07 | — | — | CN | claimed |
| CN-114933568-B | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-221334142-U | 2-Methylthio-4, 6-dichloropyrimidine synthetic equipment | 新沂大江化工有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118307483-A | Preparation method of 2-methylsulfonyl-4, 6-dimethoxy pyrimidine | 新沂大江化工有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-114933568-A | Preparation method of 4, 6-dimethyl-2-methylsulfonyl pyrimidine | 抚州润泰药业有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-112552244-A | Production process of 4, 6-dimethoxy-2-methylsulfonyl pyrimidine | 内蒙古科硕新材料科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-106866547-B | Synthesis method of 2-ethoxy-4, 6-dichloropyrimidine | 江苏省农用激素工程技术研究中心有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-105026376-B | Process for the preparation of bispyribac-sodium and intermediates thereof | 加尔达化学有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-106866547-A | The synthetic method of the dichloro pyrimidine of 2 ethyoxyl 4,6 | 江苏省农用激素工程技术研究中心有限公司 | 2017-06-20 | — | — | CN | claimed |
| EP-1490358-A4 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM (KR) | 2006-04-12 | — | — | EP | claimed |
| US-20050222150-A1 | 6-(4-substituted-anilino)pyrimidine derivates, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2005-10-06 | — | — | US | claimed |
| EP-1490358-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C Biopharm (KR) | 2004-12-29 | — | — | EP | claimed |
| US-6693194-B2 | BY REACTING 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE IN AN INERT ORGANIC SOLVENT WITH AN ALKALI METAL METHOXIDE, TRANSFERRING TO AN AQUEOUS ACID MEDIUM AND OXIDATION; USING THE PRODUCT TO PREPARE 7-((4,6- | SYNGENTA CROP PROTECTION, INC. | 2004-02-17 | — | — | US | claimed |
| WO-2003084953-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM (KR) | 2003-10-16 | — | — | WO | claimed |
| US-20030135047-A1 | Process for the preparation of 4,6-dimethoxy-2-(methylsulfonyl)-1,3-pyrimidine | SYNGENTA CORP PROTECTION, INC. | 2003-07-17 | — | — | US | claimed |
| EP-1301491-A1 | PROCESS FOR THE PREPARATION OF 4,6-DIMETHOXY-2-(METHYLSULFONYL)-1,3-PYRIMIDINE | Syngenta Participations AG (CH) | 2003-04-16 | — | — | EP | claimed |
| WO-2002008207-A1 | PROCESS FOR THE PREPARATION OF 4,6-DIMETHOXY-2-(METHYLSULFONYL)-1,3-PYRIMIDINE | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-31 | — | — | WO | claimed |
| WO-2000046212-A1 | METHOD OF PRODUCING SUBSTITUTED PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-08-10 | — | — | WO | claimed |
| EP-0267675-A2 | Modified conjugated diene polymer and process for production thereof | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1988-05-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222150-A1 | 6-(4-substituted-anilino)pyrimidine derivates, method for preparation thereof and antiviral pharmaceutical composition comprising the same | HAVCR2, NUDT1, GART | POLB 183/4885KMT2A 4775/4885MEN1 4830/4885 |
| US-20030135047-A1 | Process for the preparation of 4,6-dimethoxy-2-(methylsulfonyl)-1,3-pyrimidine | TPMT, DHODH, DPYD | POLB 1387/4885KMT2A 108/4885MEN1 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.