Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805797 | 1.00 | SDHB (0.46) | SDHBMAPTTP53ADORA2ATDP1 | |
| SCHEMBL19805863 | 0.90 | SDHB (0.49) | SDHBSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL29976766 | 0.90 | SDHB (0.49) | SDHBSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL19805642 | 0.89 | SDHB (0.48) | SDHBMAPTTP53TDP1SMN1; SMN2 | |
| SCHEMBL29976174 | 0.89 | SDHB (0.48) | SDHBMAPTTP53TDP1SMN1; SMN2 | |
| SCHEMBL29976692 | 0.82 | SDHB (0.50) | SDHBMAPTTP53ADORA2ATDP1 | |
| SCHEMBL19805660 | 0.82 | SDHB (0.50) | SDHBMAPTTP53ADORA2ATDP1 | |
| SCHEMBL19805896 | 0.81 | SDHB (0.51) | SDHBADORA2AALDH1A1 | |
| SCHEMBL19805806 | 0.81 | SDHB (0.47) | SDHBMAPTTP53ADORA2ATDP1 | |
| SCHEMBL19805811 | 0.79 | SDHB (0.71) | SDHBTP53SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |