Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 9/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805863 | 1.00 | SDHB (0.49) | SDHBCYP11B1CYP11B2SMN1; SMN2ALDH1A1 | |
| SCHEMBL29976395 | 0.90 | SDHB (0.46) | SDHBSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL19805797 | 0.90 | SDHB (0.46) | SDHBSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL29976692 | 0.87 | SDHB (0.50) | SDHBSMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL19805660 | 0.87 | SDHB (0.50) | SDHBSMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL19805896 | 0.86 | SDHB (0.51) | SDHBCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL19805642 | 0.83 | SDHB (0.48) | SDHBSMN1; SMN2ALDH1A1KDM4CHPGD | |
| SCHEMBL29976174 | 0.83 | SDHB (0.48) | SDHBSMN1; SMN2ALDH1A1KDM4CHPGD | |
| SCHEMBL19806077 | 0.82 | SDHB (0.50) | SDHBCYP11B1CYP11B2SMN1; SMN2ALDH1A1 | |
| SCHEMBL19805868 | 0.80 | SDHB (0.73) | SDHBSMN1; SMN2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |