SCHEMBL29976773

SCHEMBL29976773

CNC(=O)CCc1ccc(OCc2cc(Cl)cc3c2OC(C)(C)C3)c(C)c1C

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 19/20 0.45
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27167262 1.00 FFAR4 (0.45) FFAR4KMT2A
SCHEMBL2439273 0.90 FFAR4 (0.54) FFAR4
SCHEMBL27167263 0.90 ALDH1A1 (0.46) FFAR4KMT2A
SCHEMBL29977052 0.90 ALDH1A1 (0.46) FFAR4KMT2A
SCHEMBL2433617 0.82 FFAR4 (0.51) FFAR4
SCHEMBL9983560 0.80 FFAR4 (0.46) FFAR4KMT2A
SCHEMBL2431745 0.79 FFAR4 (0.48) FFAR4KMT2A
SCHEMBL9983702 0.79 FFAR4 (0.45) FFAR4KMT2A
SCHEMBL9983434 0.78 FFAR4 (0.51) FFAR4KMT2A
SCHEMBL9983446 0.78 FFAR4 (0.53) FFAR4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117642381-A Fatty Acid Amide Hydrolase (FAAH) cleavable prodrugs of brain targeting actives in combination with peripherally restricted FAAH inhibitors 速通医疗公司 2024-03-01 CN disclosed
WO-2022236118-A1 FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF BRAIN TARGETING ACTIVES AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS AUTOBAHN THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed