SCHEMBL27167263

SCHEMBL27167263

Cc1c(CCC(=O)NC2CC2)ccc(OCc2cc(Cl)cc3c2OC(C)(C)C3)c1C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
FFAR4 Q5NUL3 15/20 0.44
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29977052 1.00 ALDH1A1 (0.46) ALDH1A1FFAR4KMT2ALMNAHPGD
SCHEMBL27167262 0.90 FFAR4 (0.45) FFAR4KMT2A
SCHEMBL29976773 0.90 FFAR4 (0.45) FFAR4KMT2A
SCHEMBL2439273 0.87 FFAR4 (0.54) FFAR4
SCHEMBL2433617 0.79 FFAR4 (0.51) FFAR4
SCHEMBL9983560 0.77 FFAR4 (0.46) FFAR4KMT2A
SCHEMBL2431745 0.77 FFAR4 (0.48) FFAR4KMT2A
SCHEMBL9983860 0.76 FFAR4 (0.43) FFAR4
SCHEMBL9983702 0.76 FFAR4 (0.45) FFAR4KMT2A
SCHEMBL9983434 0.75 FFAR4 (0.51) FFAR4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240261414-A1 FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF BRAIN TARGETING ACTIVES AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS AUTOBAHN THERAPEUTICS INC (US) 2024-08-08 US disclosed
EP-4334283-A1 FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF BRAIN TARGETING ACTIVES AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS Autobahn Therapeutics, Inc. (US) 2024-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261414-A1 FATTY ACID AMIDE HYDROLASE (FAAH) CLEAVABLE PRODRUGS OF BRAIN TARGETING ACTIVES AND COMBINATION WITH PERIPHERALLY RESTRICTED FAAH INHIBITORS FAAH, FAAH2, FFAR1 ALDH1A1 2257/4885FFAR4 16/4885KMT2A 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.