Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 11/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985645 | 1.00 | SDHB (0.45) | SDHBTP53MAPTKMT2AMAPK10 | |
| SCHEMBL20985704 | 0.90 | SDHB (0.47) | SDHBTP53MAPT | |
| SCHEMBL29976232 | 0.90 | SDHB (0.47) | SDHBTP53MAPT | |
| SCHEMBL19805982 | 0.87 | SDHB (0.46) | SDHBTP53MAPTMAPK10KDM4E | |
| SCHEMBL20985733 | 0.87 | SDHB (0.49) | SDHBTP53MAPT | |
| SCHEMBL29975806 | 0.87 | SDHB (0.49) | SDHBTP53MAPT | |
| SCHEMBL20985681 | 0.83 | SDHB (0.54) | SDHBTP53MAPT | |
| SCHEMBL29975895 | 0.83 | SDHB (0.54) | SDHBTP53MAPT | |
| SCHEMBL20985724 | 0.83 | SDHB (0.63) | SDHBTP53MAPTKMT2AKDM4E | |
| SCHEMBL19806070 | 0.80 | SDHB (0.62) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |