Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899176 | 0.74 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL28391216 | 0.66 | MAP3K5 (0.35) | MAP3K5GRM5GRM1 | |
| SCHEMBL28388036 | 0.64 | DAO (0.40) | MAP3K5GRM5GRM1 | |
| SCHEMBL28987779 | 0.64 | MAP3K5 (0.39) | MAP3K5GRM5GRM1 | |
| SCHEMBL28394631 | 0.64 | MAP3K5 (0.39) | MAP3K5 | |
| SCHEMBL30238994 | 0.63 | MAP3K5 (0.39) | MAP3K5 | |
| SCHEMBL25236233 | 0.62 | ALDH1A1 (0.39) | — | |
| SCHEMBL28987786 | 0.62 | GRM5 (0.43) | MAP3K5GRM5GRM1 | |
| SCHEMBL22473968 | 0.60 | MAP3K5 (0.46) | MAP3K5 | |
| SCHEMBL28899189 | 0.60 | IP6K1 (0.55) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504986-B | Apoptosis signal regulating kinase inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-115504986-A | Apoptosis signal regulating kinase inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-111094250-B | Apoptosis signal regulating kinase inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-11-04 | — | — | CN | disclosed |