Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.68 |
| ▸ | PTAFR | P25105 | 1/20 | 0.68 |
| ▸ | HTR1D | P28221 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GMNN | O75496 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828992 | 1.00 | ADRA1D (0.68) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL19821628 | 0.88 | MAPT (0.71) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL30278565 | 0.88 | MAPT (0.71) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL3405063 | 0.86 | SMN1; SMN2 (0.60) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL15263707 | 0.85 | ADRA1D (0.78) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL3409969 | 0.84 | SMN1; SMN2 (0.67) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL30649908 | 0.84 | SMN1; SMN2 (0.67) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL17761142 | 0.84 | SMN1; SMN2 (0.68) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL6904233 | 0.84 | SMN1; SMN2 (0.68) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL29458110 | 0.84 | SMN1; SMN2 (0.68) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115128287-A | Markers for acid sphingomyelinase disorders and uses thereof | 建新公司 | 2022-09-30 | — | — | CN | disclosed |