Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GMNN | O75496 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | AKT1 | P31749 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKCB | P05771 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17761142 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL29458110 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL8586988 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL29977369 | 0.84 | ADRA1D (0.68) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL3828992 | 0.84 | ADRA1D (0.68) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL30955383 | 0.83 | FABP3 (0.49) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL29395054 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL3405063 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL63754 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMAPK1MEN1GMNN | |
| SCHEMBL245306 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMAPK1MEN1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040052837-A1 | Lipid conjugated anti-cancer drugs and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-03-18 | — | — | US | disclosed |