SCHEMBL29977611

SCHEMBL29977611

c1ccc(C2CCCN2)nc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.50
CHRNA4 P43681 3/20 0.50
CHRNA7 P36544 2/20 0.50
MEN1 O00255 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C19 P33261 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
CYP2C9 P11712 1/20 0.45
CHRM5 P08912 3/20 0.43
CHRM3 P20309 3/20 0.43
CHRM1 P11229 2/20 0.43
CHRM2 P08172 2/20 0.43
CHRM4 P08173 2/20 0.43
TAAR1 Q96RJ0 2/20 0.42
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20707 1.00 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
SCHEMBL3925606 1.00 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
SCHEMBL30824585 1.00 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
SCHEMBL3926825 1.00 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
Hydrochloric Acid SCHEMBL28366949 0.98 CHRNB2 (0.49) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
Hydrochloric Acid SCHEMBL2039471 0.98 CHRNB2 (0.49) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
Hydrochloric Acid SCHEMBL31095337 0.98 CHRNB2 (0.49) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
Hydrochloric Acid SCHEMBL28366948 0.98 CHRNB2 (0.49) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
SCHEMBL3536308 0.95 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7MEN1CYP2D6
SCHEMBL3163175 0.95 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118356774-B Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof 江苏创新石化有限公司 2025-02-14 CN claimed
CN-118356774-A Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof 江苏创新石化有限公司 2024-07-19 CN claimed
CN-118356774-B Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof 江苏创新石化有限公司 2025-02-14 CN disclosed
CN-118356774-B Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof 江苏创新石化有限公司 2025-02-14 CN disclosed
CN-115894447-B METTL3 inhibitors and uses thereof 成都先导药物开发股份有限公司 2024-10-01 CN disclosed
CN-118356774-A Low-energy-consumption high-selectivity composite desulfurization solvent and preparation method thereof 江苏创新石化有限公司 2024-07-19 CN disclosed
US-20230133132-A1 NAMPT MODULATORS CYTOKINETICS, INC. 2023-05-04 US disclosed
CN-115894447-A METTL3 inhibitors and uses thereof 成都先导药物开发股份有限公司 2023-04-04 CN disclosed
CN-110627812-B Heterocyclic compounds as TRK inhibitors 北京诺诚健华医药科技有限公司 2022-10-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133132-A1 NAMPT MODULATORS NAMPT, MC4R, SIRT1 CHRNB2 2815/4885CHRNA4 2484/4885CHRNA7 2536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.