Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.33 |
| ▸ | GABRP | O00591 | 4/20 | 0.33 |
| ▸ | GABRD | O14764 | 4/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.33 |
| ▸ | GABRE | P78334 | 4/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24666958 | 0.92 | SRC (0.49) | SRCFGFR1GABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL29977680 | 0.91 | SRC (0.48) | SRCFGFR1GABRA1GABRG2GABRB3 | |
| SCHEMBL29977131 | 0.88 | FGFR1 (0.38) | SRCFGFR1GABRA1GABRG2GABRB3 | |
| SCHEMBL24666732 | 0.88 | FGFR1 (0.38) | SRCFGFR1GABRA1GABRG2GABRB3 | |
| SCHEMBL24666788 | 0.84 | SRC (0.39) | SRCFGFR1FGFR4LYNBTK | |
| SCHEMBL29977440 | 0.84 | SRC (0.39) | SRCFGFR1FGFR4LYNBTK | |
| SCHEMBL24666730 | 0.81 | ABL1 (0.47) | — | |
| SCHEMBL29977525 | 0.81 | ABL1 (0.47) | — | |
| SCHEMBL30780116 | 0.81 | GABRA1 (0.32) | SRCFGFR1GABRA1GABRG2GABRB3 | |
| SCHEMBL27148013 | 0.81 | GABRA1 (0.32) | SRCFGFR1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236319-A1 | NAPHTHYRIDONE COMPOUNDS FOR INHIBITION OF RAF KINASES AND/OR BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |