SCHEMBL29978152

SCHEMBL29978152

Cc1ccccc1C(=O)N1CCc2sc(-c3noc(C(F)(F)F)n3)cc2C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
HTT P42858 1/20 0.47
HDAC4 P56524 12/20 0.43
HDAC6 Q9UBN7 5/20 0.43
HDAC8 Q9BY41 3/20 0.43
HDAC2 Q92769 1/20 0.43
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HDAC1 Q13547 1/20 0.40
HSD11B1 P28845 1/20 0.39
HDAC7 Q8WUI4 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
BCL2 P10415 1/20 0.38
BAD Q92934 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29977922 0.93 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9HPGDCYP2C19
SCHEMBL29978336 0.90 HDAC6 (0.44) ALDH1A1HDAC4HDAC6HDAC8HDAC2
SCHEMBL29978387 0.88 HDAC4 (0.50) HTTHDAC4HDAC6HDAC8HDAC2
SCHEMBL29977801 0.87 HDAC4 (0.39) ALDH1A1CYP2C9HPGDCYP2C19HDAC4
SCHEMBL29978301 0.86 HDAC4 (0.52) HDAC4HDAC6HDAC8HDAC2HDAC1
SCHEMBL29978176 0.86 GRM5 (0.45) CYP3A4HPGDHDAC4HDAC6HDAC8
SCHEMBL29978326 0.85 HDAC4 (0.44) HDAC4HDAC6HDAC8HDAC2HDAC1
SCHEMBL29978909 0.84 HDAC4 (0.48) HDAC4HDAC6HDAC8HDAC2HDAC1
SCHEMBL29978497 0.84 HDAC4 (0.44) HDAC4HDAC6HDAC8HDAC2HDAC1
SCHEMBL29977967 0.83 HDAC4 (0.50) HDAC4HDAC6HDAC8HDAC2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022234470-A1 NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2022-11-10 WO claimed
WO-2022234470-A1 NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2022-11-10 WO disclosed